Functional Neuroimaging
Positron Emission Tomography (PET) scans, are able to take images of your brain. PET works by measuring the amount of a radioactive tracer as it is transported in your body. The radioactive tracer used in the Sleep Neuroimaging Research Program studies is F-fluorodeoxyglucose (F-FDG). The use of F-FDG in these research studies is considered generally safe and effective as approved by the University of Pittsburgh Radioactive Drug Research Committee in accordance with Food and Drug Administration regulations. The F-FDG is very similar to glucose and is transported into the cells of your body using the same mechanisms as normal glucose. Your brain uses glucose as a source of energy (metabolism). As part of each PET study, you will be asked to lie very still on a table very similar to the one used in a typical CT scan. For the purpose of positioning your head in the scanner, an individually molded, thermoplastic head holder will be made for you to wear during the scanning procedure. After your head has been positioned, continuous scanning will take place for approximately 30 minutes.
PET Scan MRI Scan
Magnetic Resonance Imaging Scans are commonly referred to as MRI scans. MR machines use a large magnet to take a picture of brain anatomy. The MR machine used in the Sleep Neuroimaging Research Program is closed. Therefore, if you have a fear of tight closed spaces or suffer from claustrophobia you may be excluded from participating in these research studies. If you experience a fear of the confined space while in the MR machine, you can end the study. The MRI scan will last approximately 15 to 30 minutes. There are certain conditions which would exclude you from having an MR study. These conditions include heart pacemaker, aneurysm clip, ear implant, IUD, shrapnel, neurostimulators or other metal devices. The MR procedure could result in movement of any metal objects in the body, and this movement could result in serious injury. Dental fillings do not present a problem. Pregnancy may also exclude you from this study. Your MRI will be scheduled prior to starting the sleep studies.
